While an increase in MEG8, MEG9 and MIR381HG miRNA precursors was consistently seen in epithelial-derived cell lines, we did not see induction of these lncRNAs upon reactivation of Burkitt’s lymphoma cell lines (Fig 6G), suggesting that the activation of transcripts in the DLK1-DIO3 locus is specific to EBV infection of epithelial cells. Here, DIO3 is linked to Epstein-Barr virus infection.