PRF1 and neoplasm: To investigate the immunological consequences of MET activation in PDAC, we re‐analyzed the relationship between p‐MET expression and the functional states of tumor‐infiltrating CD8+ T cells (activation and exhaustion).[20] Intriguingly, flow cytometry analysis revealed that p‐MET‐high tumors exhibited significantly reduced cytotoxic function, as indicated by decreased expression of GzmB (p = 0.009) and perforin (p < 0.001) (Figure 1E; Figure S3A, Supporting Information).