By capturing the transcriptomic profiles of individual cells, scRNA‐seq enables precise characterization of malignant and immune cell states, facilitates the identification of prognostic markers such as AIMP1 and CNIH4 in HNSCC, and reveals novel functional roles of key regulators such as the VGSC β3 subunit in glioma.179, 180, 181. Here, AIMP1 is linked to head and neck squamous cell carcinoma.