In a Salmonella-induced colitis model, BB-12 was shown to alleviate inflammation by modulating the relative expression of the colonic cytokines IL-1β, TNF-α and CXCL2, and reducing the secretion of IL-1β, IL-6, and TNF-α in serum and colonic tissues (Pang et al., 2021). The gene discussed is IL1B; the disease is colitis.