In detail, although the IL-10 -592 was significantly linked to periodontitis risk in the overall population, IL-10 -819 genetic variations were associated with periodontitis only in specific ethnicities.73 According to Petkovic-Curcin et al,38 the prevalence of IL-10 -1082 polymorphic genotypes was different between PI patients and healthy controls. Here, IL10 is linked to periodontitis.