LSR and bacterial urinary tract infection: The observation that global gene expression of UPEC strains in vivo during human UTI (hUTI) or murine UTI (mUTI) was more similar to their in vitro gene expression in LB than to their in vitro gene expression in pooled human urine (Frick-Cheng et al., 2020) allows us to assess the importance of lsr-dependent gene expression for colonization of the urinary bladder using our own in vitro RNA-seq data in LB.