INS and atherosclerosis: KEGG enrichment analysis revealed that DE-AGs were associated with pathways such as insulin resistance, type II diabetes mellitus, insulin signalling, regulation of lipolysis in adipocytes, cortisol synthesis and secretion, lipid and atherosclerosis, IL-17 signalling pathway, aldosterone synthesis and secretion, NF-kappa B signalling pathway, Toll-like receptor (TLR) signalling pathway, etc. (Figure 2I).