In most hematological tumors, FOXP1 expression demonstrated a positive correlation with the expression levels of stimulatory immune genes such as ICOSLG, IL2RA, and HMGB1, and a negative correlation with the expression levels of inhibitory immune genes, such as SLAMF7 (Figure 4C). Here, HMGB1 is linked to hematopoietic and lymphoid cell neoplasm.