In a multiple logistic regression analysis, the independent predictors of IGF2BP3 expression in breast cancer were TNBC status (odds ratio = 3.408; 95% confidence interval: 1.026–11.321; P=0.045) and axillary lymph node metastasis (0.200; 0.068–0.593; P=0.004). Here, IGF2BP3 is linked to breast cancer.