IGF2BP3 and breast carcinoma: The ROC curve analysis showed that the area under the curve (AUC) for IGF2BP3 positive prediction of breast cancer was 0.557 (95% CI 0.483–0.631; P=0.164; Figure 2A), with a sensitivity of 11.4%, specificity of 100.0%, PPV of 100.0%, and NPV of 18.5%.