PF4 and intracerebral hemorrhage: Specifically, Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT) and Spontaneous Heparin-Induced Thrombocytopenia (S-HIT) are characterized by the excessive inflammatory response driven by the formation of PF4-antibody complexes, which not only promote thrombosis but can also lead to severe complications such as intracerebral hemorrhage.