Positive correlations were found between TNF-α and PD duration (r = 0.689, p < 0.01), IL-1β and PDQ-39 score (r = 0.462, p < 0.05) and IL-10 and HAMD score (r = 0.512, p < 0.05); however, negative correlations were found between IL-6 and UPDRS III score (r = −0.497, p < 0.05) and IFN-γ and SCOPA-AUT score (r = −0.588, p < 0.01). This evidence concerns the gene TNF and Parkinson disease.