NF2 and colorectal cancer: It has been implicated in Wnt-driven proliferation in colorectal cancer and leukemia (18, 21–23) and contributes to tumorigenesis in lung squamous cell carcinoma by phosphorylating TCF4/TCF7L2 and neurofibromin 2 (NF2) at serine 13 (S13) (18, 21, 24–28).