This study identified ten key genes (ACTB, RAC1, IQGAP1, FLNB, MYL6, ABI2, DBN1, PRDX1, SLC2A1, and SLC2A3) implicated in acute myocardial infarction through various bioinformatics approaches. The gene discussed is SLC2A3; the disease is acute myocardial infarction.