SOAT1 and Parkinson disease: Caboni et al. (2004) suggested that the Parkinsonian effects of deguelin primarily arise from the inhibition of mitochondrial complex I within the respiratory chain. In a similar vein, Kim et al. (2008) indicated that deguelin not only induces symptoms akin to Parkinson’s disease (PD) but also influences the Src/signal transducers and activators of transcription (STAT) signaling pathway.