MUC1 and prostate neoplasm: In translational models, PPI potently suppressed CRPC growth and induced G1/S phase arrest in both xenograft models and primary cell cultures.PPI concomitantly reduced p65 phosphorylation, mucin 1 (MUC1) oncoprotein levels, and long non-coding RNA HOTAIR expression.These findings establish PPI as multimodal inhibitors that disrupt NF-κB/p65-MUC1 signaling crosstalk in stroma-rich prostate tumors (Xiang et al., 2018).