IL6 and cancer: STRING network and pathway analysis showed that the inner dura and arachnoid barrier shared the expression of genes involving a strong IL6-central inflammatory/fibrotic network, PI3K/AKT-, WNT-, and VEGFA/VEGFR2-signaling, developmental biology and axon guidance signatures, EGF-IL6-WNT5A-central cancer pathways, and an IL1B-FN1-central immune network (SFig. 5G).