Reduced infections: probiotics lowered septicemia (59% vs. 88%, p=0.008), urinary infections (2% vs. 13%, p=0.017), and diarrhea (24% vs. 46%, p=0.012). Biomarkers: decreased serum zonulin (0.42 vs. 1.36 ng/mg, p<0.001) and endotoxin (p<0.001). Liver function: improved ALT/AST levels (p<0.05). Hospital outcomes: shorter pyrexia duration (6.02 vs. 6.98 days, p=0.006) and hospital stay (11.26 vs. 12.96 days, p<0.001). The gene discussed is GPT; the disease is infection.