Univariate Cox regression analysis identified sex, age, smoking, diabetes, BNP, Ccr, TSH, FT4, TSHI, TT4RI, TFQI, PTFQI, MVD, diuretics, and insulin as significant risk factors for MACCEs following PCI in patients with ACS (all P<0.05, to avoid mutual interference between the thyroid hormone sensitivity indices, separate tables were created for these variables (refer to the Supplementary Tables 1-4). This evidence concerns the gene NPPB and diabetes mellitus.