In a previous study, depletion of polysialylated NCAM1 (PSA-NCAM) was observed in dorsolateral prefrontal cortex of post-mortem samples in individuals with schizophrenia, and this change was not observed in cases of BD or MDD (Gilabert-Juan, Varea et al. 2012). This evidence concerns the gene NCAM1 and Behcet disease.