NLRP3 and rheumatic disorder: A positive correlation was found between NLRP3 inflammasome expression levels and activity index scores in systemic lupus erythematosus (SLE) patients, that nucleic acid components could activate NLRP3 inflammasome in human monocytes in vitro, which active caspase‐1 was upregulated in monocytes from SLE patients compared to patients with other rheumatic diseases, and that serum titers of anti‐double‐stranded DNA antibodies in monocytes were positively correlated with active caspase‐1 [52].