ARID1B and neoplasm: This is where ARID1B may become dominant over mutated ARID1A, promoting tumor survival.[13, 22, 23, 24, 27] The mutual exclusion observed between ARID1A and ARID1B in tumor cells highlights their complex interplay and the importance of proper regulation in maintaining cellular homeostasis versus promoting tumorigenesis.[11, 13, 18, 23, 24, 25] Ongoing research aims to further elucidate the precise mechanisms regulating ARID1A and ARID1B, including transcriptional control, nuclear translocation, and their roles within the SWI/SNF complex in chromatin remodeling and other functions.