ARID1B achieves this by linking the BAF complex to chromatin and facilitating the recruitment of regulatory factors to DNA.[12, 13, 14, 15, 16, 17, 18, 19] Both mutations and dysregulation of genes encoding components of the SWI/SNF complexes, including ARID1B, have been implicated in various malignancies, including breast cancer.[13, 20, 21, 22, 23, 24] Results from recent pathological studies based on patient cohorts indicated that elevated accumulation of ARID1B in breast tumors is associated with poor prognosis.[25, 26]. The gene discussed is ARID1B; the disease is breast cancer.