TNF and breast cancer: Pathway enrichment analysis revealed that genes upregulated by ARID1B OE were significantly enriched in pathways frequently linked to oncogenic processes in breast cancer and other malignancies, including epithelial–mesenchymal transition (EMT), TNFα signaling via NFκB, inflammatory response, interferon alpha response, interferon gamma response, and IL6/JAK/STAT3 signaling (Figure 4D).