IL6 and acute myeloid leukemia: This was consistent with Ahmed et al., Liu et al. & Zhang et al. [12, 24, 25] This was explained by the secretion of numerous inflammatory markers, including IL-6, from AML blasts, which contribute to the depletion of normal hematopoietic progenitors and the induction of endothelial remodelling [21, 23, 26].