MAPT and dementia: At the median age of 71 years, the prevalence estimates of tau positivity in the temporal cortex were higher in Aβ-positive women compared with Aβ-positive CU men (mean difference 5.2% (95% CI 1.7–8.8%), P = 0.001), MCI (mean difference 8.2% (95% CI 2.1–14.3%), P = 0.003) and dementia (mean difference 8.1% (95% CI 4.6–11.6%), P < 0.001).