MAPT and dementia: The interaction between sex and Aβ status on the prevalence of tau positivity was not significant in the MCI and dementia groups, but there were significant main effects of sex on tau positivity in the MCI (β = 0.34, P < 0.001) and dementia (β = 0.59, P < 0.001) groups (Fig. 3f and Supplementary Table 7).