VEGFA and endothelial dysfunction: Although the risk of NV was not significantly associated in their study (possibly due to limited follow-up duration) [4], the association between NV and OSA seen in our study is consistent with the well-established understanding that recurrent episodes of nocturnal hypoxia and reperfusion in OSA lead to pathological production of VEGF and oxidative stress that leads to endothelial dysfunction [4, 37, 38].