EIF4EBP1 and Mobius syndrome: Analysis of EIF4EBP1 mRNA expression levels according to MB groups showed, in two single patient cohorts [8, 38] as well as in a pooled patient cohort [7, 39–41], that EIF4EBP1 mRNA expression was elevated in Group 3 relative to Group 4 MBs (Fig. 1B, C; Supplementary Fig. 1E; Table S8), in accordance to previous observations made for 4EBP1 protein levels using proteomics data [35].