C (Supplemental Fig. S2F, Fig. 5G), but no pathways were significantly enriched in Res Cl B. MAPK1 and MAPK3 signaling is known to affect cancer cell migration and metastasis (67), while Rho GTPases also affect cell motility (68), which may also not be directly linked to Olaparib resistance. This evidence concerns the gene MAPK1 and cancer.