CCL2 and chronic atrophic gastritis: For instance, Li et al’s [11] network analysis revealed that the leptin biomarker indicated low levels of energy metabolism in patients with cold syndrome, while the human monocyte chemoattractant protein-1 (CCL2/MCP1) biomarker suggested intensified immune regulation in patients with hot syndrome, based on a study involving patients with chronic superficial gastritis and chronic atrophic gastritis.