Patients with sarcoma (SAR), UCEC, STAD, SKCM, ESCA, Liver Hepatocellular Carcinoma (LHC), BLCA, COAD, CESC, MESO, LUAD, LUSC, HNSC, PRAD, KIRP, OV, BRCA, AML, Brain Lower Grade Glioma (LGG), GBM, and KIRC carried SREBF1 mutation. The gene discussed is SREBF1; the disease is acute myeloid leukemia.