We found that high expression of SREBF1 associated with poor OS in BLCA (p = 0.016), Mesothelioma (MESO) (p = 0.041), Acute Myeloid Leukemia (LAML) (p = 0.011), and patients with high SREBF1 expression in COAD exhibited significantly inferior disease-free survival (DFS) (p = 0.029) (Fig 2B and S1A Fig). Here, SREBF1 is linked to mesothelioma.