Additionally, miR-423-5p regulates hepatic metabolism by repressing FAM3A [53], while miR-9, whose levels increase with the severity of MASLD, may affect several key genes, such as SIRT1 and CoREST, promoting disease progression, which were recognized for their roles in liver metabolism, inflammation, and stress response [54]. The gene discussed is SIRT1; the disease is metabolic dysfunction-associated steatotic liver disease.