Due to their histological similarities and shared molecular characteristics, there is a growing tendency to consider these entities as part of the same tumor spectrum under the collective designation of "MYB- or MYBL1-altered pLGGs [20]." While these two types of MYB- or MYBL1-altered pLGGs are more common in children (median age 5–13 years), there has been an increasing number of reports in patients over 18 years of age [20, 22]. The gene discussed is MYB; the disease is neoplasm.