CHRNA7 and Parkinson disease: In-vivo studies performed on hemiparkinsonian and Parkinson’s rat models have shown that the activation of α7nAChRs with specific agonists like galantamine and nicotine attenuated neuroinflammation and toxin-induced loss of dopaminergic neurons (Yanagida et al. 2008; Stuckenholz et al. 2013; Quik et al. 2015; Metzner et al. 2022).