CD8A and neoplasm: Within the TME, cDC1s include at least three functionally distinct subpopulations that coordinate antitumor immunity: immature cDC1s, characterized by low MHCII expression and located within the tumor parenchyma; activated, nonmigratory cDC1s, which display high MHCII expression and lack CCR7, participating in the organization of stromal CD8+ T cell niches by secreting CXCL9; and migratory, immunoregulatory cDC1s that also express high levels of MHCII but are CCR7‐positive.