Ursolic acid inhibits KC pyroptosis in liver fibrosis in vitro and in vivo by suppressing the protein expression of pyroptosis-related indicators (NLRP3, pro-caspase-1, cleaved caspase-1, GSDMD, GSDMD-N, and IL-1β) in the NOX2/NLRP3 inflammasome signaling pathway [34]. This evidence concerns the gene NLRP3 and keratoconus.