Through logistic regression analyses, we investigated the relationship between body composition markers (PFI, SFI, SMI) and systemic immune-nutritional scores (CAR, PNI, SII, GPS, NLR, PLR), while adjusting for age, sex, PNI, SII, PLR, NLR, CAR, GPS, tumor histology, ECOG performance status, smoking status, radiation treatment sites, BMI, hypertension, hyperglycemia, albumin levels, triglycerides, cholesterol, HDL, and LDL. This evidence concerns the gene ALB and neoplasm.