The six distinct regions identified included (i) separate tumor and (ii) dysplastic zones, (iii) mucin signaling hotspots (glycoprotein-rich areas linked to specific colorectal cancer phenotypes [64]), (iv) tumor stroma, (v) cellular detritus split off from the tumor, and (vi) an external region (likely diffusion artifacts) outside the tissue (Figure 5F). This evidence concerns the gene MUC5AC and neoplasm.