Elevated NLRP3 inflammasome components in AD retinas correlated with retinal Aβ42 and oligo-tau levels, closely linked to degeneration markers and retinal atrophy, suggesting that Cp infection induces a localized inflammatory response in the retina, mirroring inflammatory processes in the brain that contribute to neurodegeneration13,154–158. Here, NLRP3 is linked to Alzheimer disease.