This study aimed to investigate the cytotoxic effects of dichloromethane (CHD) and methanol (CHM) extracts from the endemic C. lycaonica species on HeLa human cervical cancer cells, with a focus on elucidating the apoptotic mechanisms through the assessment of caspase‐3 and caspase‐9 activities, as well as the Bax/Bcl‐2 ratio, and to identify the bioactive compounds responsible for these effects using LC‐HRMS analysis. Here, BAX is linked to cervical carcinoma.