Notably, 6 patients (11.8%) experienced grade ≥3 AEs, including leukopenia (n=1, 2.0%), neutropenia (n=1, 2.0%), thrombocytopenia (n=2, 3.9%), elevated ALT (n=2, 3.9%), elevated AST (n=2, 3.9%), hypoalbuminemia (n=2, 3.9%), hyperbilirubinemia (n=1, 2.0%). This evidence concerns the gene GPT and Hyperbilirubinemia.