Accordingly, we screened for models characterized with stroma vessel type tumors and identified two human pancreatic cancer cell lines, Capan-1 and BxPC-3, both of which exhibited high CD44v6 expression (Supplementary Figure 7A) and detectable LGR7 expression, the cognate receptor for RLN2 (Supplementary Figure 7B). This evidence concerns the gene RLN2 and familial pancreatic carcinoma.