Accordingly, we screened for models characterized with stroma vessel type tumors and identified two human pancreatic cancer cell lines, Capan-1 and BxPC-3, both of which exhibited high CD44v6 expression (Supplementary Figure 7A) and detectable LGR7 expression, the cognate receptor for RLN2 (Supplementary Figure 7B). Here, RLN2 is linked to pancreatic neoplasm.