IGHG3 and infection: As strong surrogates of protection, the IgM, IgG, IgG1, IgG2a, IgG2b, and IgG3 antibody absorbance values after infection were negatively and significantly correlated with the relative weights of the spleens (Supplementary Figures S4a–f) and livers (Supplementary Figures S4g–1) (Table 1).