The F3 and the two dosages of the F1F3 vaccine, which were the most potent, exhibited absorbance increases after infection, with a range of 42%–49% for IgA, 41%–69% for IgM, 145%–122% for IgG, 84%–103% for IgG1, 84%–78% for IgG2a, 55%–58% for IgG2b, and 131%–69% for IgG3. Here, IGHG3 is linked to infection.