Break-apart FISH analysis was performed in 1,087 cases demonstrating informative results in Table 2; Figures 1–6, including 94 ARMS, 61 CCS, 497 Ewing sarcoma/round cell sarcoma with EWSR1-non-ETS fusions, 19 LGFMS, 209 NF and 207 SS. The gene discussed is EWSR1; the disease is Ewing sarcoma.