The majority of studies on perinatal cerebral infarction have focused on the risk factors and prognosis of arterial ischemic infarction, and the risk factors of hemorrhagic infarction have not yet been reported in large samples and multicenters, and some studies (21–23) have mentioned that hemorrhagic infarction has been associated with protein C and protein S deficiencies, maternal immune disorders, and thrombosis. This evidence concerns the gene PROS1 and deep vein thrombosis.