FLNC and myofibrillar myopathy: Pat.26 with the homozygous VUS p.(Ala12Thr) was previously published with a VUS in FLNC thought to be the cause of the myofibrillar myopathy in the proband.49 After the publication, the FLNC variant (p.(Thr2419Met)) has been reported as ‘likely benign’ in multiple submissions in ClinVar (VCV000712192.18).