Moreover, the correlations between module eigengenes and phenotype of interest were indicated as a heatmap plot (Figure 4B). Accordingly, we selected RP11-109D20.2 which was the only upregulated novel lncRNA among the top ten genes connected to MYH15 (a key hub gene in CRC development) based on WGCNA (Figure 4C). Here, MYH15 is linked to colorectal carcinoma.