SOD1 and metabolic dysfunction-associated steatotic liver disease: Multiple studies have demonstrated that anti-oxidant enzyme activity is suppressed while MDA levels increase in DM rats and patients with NAFLD.(40–42) Our results align with previous studies, showing significant increases in GSH-Px, SOD, and CAT levels and a significant decrease in MDA levels in the liver tissue of DM rats and FFA-induced HepG2 cells after EGK treatment.