In postmortem cerebral cortex samples, a positive correlation between various CYP-derived oxylipins and clinical phenotypes of AD were found, including 5-, 9-, and 12-HETE, 12-HEPE, 13-HpODE, 5,6- and 11,12-DHET, and 14,15-DiHETE (Kurano et al., 2022). Here, PPIG is linked to Alzheimer disease.