NTRK1 and cancer: Targeted therapy, which focuses on specific tumor types and minimizes damage to healthy tissues, has revolutionized cancer treatment.[16] A common overexpressed receptor, extensively studied and closely associated with the progression and malignancy of various cancers, is the epidermal growth factor receptor (EGFR).[17] EGFR is a tyrosine kinase receptor that plays a crucial role in promoting cell proliferation, survival, and angiogenesis.