Moreover, intravenous transfer of CD45+ EPCs from cachexic HCC mice to tumour‐free mice caused elevation of Mmp9 autoantibodies in the serum (Figure 6E) and marked production of autoantibodies against the lung, liver, intestine, salivary gland, pancreas and spleen (Figures 6F and S8C). This evidence concerns the gene PTPRC and hepatocellular carcinoma.