CDH1 and neoplasm: The possible mechanisms include: i) Inhibition of autophagy reduces the degradation rate of accumulated LDs, thereby limiting the energy supply required for cell invasion and migration[33]; ii) The increased autophagy flux induced by FLNs degrades more E‐cadherin proteins, leading to reduced cell surface E‐cadherin level and thus weakening the tumor metastasis suppressor effect of E‐cadherin.[34]