Previous studies have established that long non‐coding RNAs (lncRNAs) can directly interact with downstream target proteins, modulating their ubiquitination levels and thereby influencing tumor progression.[30, 31, 32, 33] In the present study, the regulatory effect of LncDARS‐AS1 on ATP1A1 was examined using dual‐luciferase reporter assays and Western blotting. This evidence concerns the gene ATP1A1 and neoplasm.