Mechanistically, LncDARS‐AS1 binds to RBM39 and disrupts its interaction with the E3 ubiquitin ligase RNF147, thereby preventing RBM39 ubiquitination and degradation, ultimately facilitating malignant progression.[10] Broad expression of LncDARS‐AS1 has been observed across various cancer types, with elevated levels consistently associated with unfavorable prognosis. The gene discussed is RBM39; the disease is cancer.